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For the purposes of the game, the circulatory system will be approximate; the player needs to be aware of her target location in the body and the name of the vessel that leads in that direction (the game tells her this), whether inside an artery or a vein. With each revolution around the body the player will pass through the heart; a cavernous, magnificent and tumultuous space. This will be a roller-coaster ride with tricuspid, mitral, aortic and pulmonary valves opening and closing 80 times per minute, and through which she will have to pass to continue her journey, propelled at speed by the blood out into the aorta and round again. As the host organism is infected and becomes sick, the temperature will rise and the heart rate will increase gradually to 120 beats per minute with obvious implications for the player. The number and types of blood cells, phagocytes and antibodies will change as the game unfolds. After two successful cell infections, the tissue around the organ will become inflamed. This will have two effects on the game. Inflammation creates increased blood flow and permeability of the vessel walls. Hence the player is propelled at speed through a dangerous area with many gaping holes. The player might pop out through a hole and for the purposes of the game she will die and have to take control of another nearby virion. This counts as a player death and will be penalized accordingly. Thus, players will face greater challenges when trying to attack an already-infected organ. The insides of the cell will also be somewhat generic, containing receptors, a nucleus, mRNA, and proteins. Players latch on to receptors, collect proteins, and attack nucleii (depending on the type of virus; see documentation for more information).
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Setting:
The Human body.